Biotransformation: Prodrugs and Cytochrome P450 and its Interactions
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چکیده
Excretion of the unchanged form of the drug is one way to terminate the action of the drug. Another way is to chemically alter it. This process is called biotransformation and is primarily for lipid-soluble drugs that cannot be eliminated unchanged by the kidney (as they readily cross the cell membranes and have considerable tubular reabsorption). In this article, we will study about various type of metabolic reactions of drugs and factors affecting the biotransformation reactions.
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